Mankin HJ. The reaction of articular cartilage to injury and osteoarthrosis (first of two parts). N Engl J Med 1974;291:1285-92.
Mankin HJ. The reaction of articular cartilage to injury and osteoarthrosis (second of two parts). N Engl J Med 1974;291:1335-40.
Pak CY, Kaplan R, Bone H et al. A simple test for the diagnosis of absorptive, resorptive and renal hypercalciurias. N Engl J Med 1975;292:497-500.
Waldvogel FA, Vasey H. Osteomyelitis: the past decade. N Engl J Med 1980;303:360-70.
Mathes SJ. The muscle flap for management of osteomyelitis. N Engl J Med 1982;306:292-5.
Reichel H, Koeffler HP, Norman AW. The role of vitamin D endocrine system in health and disease. N Engl J Med 1989;320:980-91.
Hollister DW, Godfrey M, Sakai LY et al. Immunologic abnormalities of the microfibrillar system in the Marfan Syndrome. N Engl J Med 1990;323:152-9.
Leape LL, Brennan TA, Laird N et al. The nature of adverse events in hospitalized patients (second of two parts). N Engl J Med 1991;324:377-84.
Classen DC, Evans RS, Pestotnik SL et al. The timing of prophylactic administration of antibiotics and the risk of surgical wound infection. N Engl J Med 1992;326:281-6.
Brittberg M, Lindahl A, Nilsson A et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994;331:889-95.
Pinals RS. Polyarthritis and fever. N Engl J Med 1994;330:769-74.
Lew DP, Waldvogel FA. Osteomyelitis. N Engl J Med 1997;336:999-1007.
White MP, Obrecht SE, Finnegan PM et al. Osteoprotegerin deficiency and Juvenile Paget’s Disease. N Engl J Med 2002;347:175-84.
2003
Wooley DE. The mast cells in inflammatory arthritis. N Engl J Med 2003;348:1709-11.
Richardson PG, Barlogie B, Berenson J et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003;248:2609-17.
Whyte MP, Wenkert D, Clements KL et al. Bisphosphonate-induced osteopetrosis. N Engl J Med 2003;349:457-63.
Shattuck TM, Valimaki S, Obara T et al. Somatic and germline mutations of the HRPT2 gene in sporadic parathyroid carcinoma. N Engl J Med 2003;349:1722-9.
2004
MacLaughlin DT, Donahoe PK. Sex determination and differentiation. N Engl J Med 2004;350:367-78.
Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med 2004;350:482-92.
Shane E, Adesso V, Namerow PB et al. Alendronate versus calcitriol for the prevention of bone loss after cardiac transplantation. N Engl J Med 2004;350:767-76.
Bone HG, Hosking D, Devogelaer JP et al. Ten years’ experience with alendronate for osteoporosis in postmenopausal women. N Engl J Med 2004;350:1189-99.
Block GA, Martin KJ, de Francisco ALM et al. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med 2004;350:1516-25.
Roodman GD. Mechanisms of bone metastasis. N Engl J Med 2004;350:1655-64.
van Meurs JBJ, Dhonukshe-Rutten RAM, Pluijm SMF et al. Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med 2004;350:2033-41.
Mclean RR, Jacques PF, Selhub J et al. Homocysteine as a predictive factor for hip fracture in older person. N Engl J Med 2004;350:2042-9.
Raisz LG. Homocysteine and osteoporotic fracture –culprit or bystander ? N Engl J Med 2004;350:2089-90.
Pietrangelo A. Hereditary hemochromatosis – A new look at am old disease. N Engl J Med 2004;350:2383-97.
Welt CK, Chan JL, Bullen J et al. Recombinant human leptin in women with hypothalamic amenorrhea. N Engl J Med 2004;351:987-97.
Debers JD, Tindall DJ. Mechanisms of androgen-refractory prostate cancer. N Engl J Med 2004;351:1488-90.
Zimmerli W, Trampuz A, Ochsner PE. Prostetic-joint infections. N Engl J Med 2004;351:1645-54.
Tolar J, Teitelbaum SL, Orchard PJ. Osteopetrosis. N Engl J Med 2004;351:2839-49.
2005
Shahinian VB, Kuo Y-F, Freeman JL et al. Risk of fracture after androgen deprivation for prostate cancer. N Engl J Med 2005;352:154-64.
Steward AF. Hypercalcemia associated with cancer. N Engl J Med 2005;352:373-9.
Silverman E, Mouy R, Spiegel L et al. Leflunomide or methotrexate for juvenile Rheumatoid Arthritis. N Engl J Med 2005;352:1655-66.
Liu Y-F, Chen W-M, Lin Y-F et al. Type II collagen gene variants and inherited osteonecrosis of the femoral head. N Engl J Med 2005;352:2294-2301.
Eghbali-Fatourechi GZ, Lamsam J, Frase D et al. Circulating osteoblast-lineage cell in humans. N Engl J Med 2005;352:1959-66.
Canalis E. The fate of circulating osteoblasts. N Engl J Med 2005;352:2014-6.
Maerevoet M, Martin C, Duck L. Osteonecrosis ofthe iaw and bisphosphonates. N Engl J Med 2005;353:99-102.
Raisz LG. Screening for osteoporosis. N Engl J Med 2005;353:164-71.
Karsenty G. An aggrecanase and osteoarthritis. N Engl J Med 2005;353:522-3.
Black DM, Bilezikian JP, Ensrud KE et al. One year of alendronate after one year of parathyroid hormone (1-84) for osteoporosis. N Engl J Med 2005;353:555-65.
Cosman F, Nieves J, Zion M et al. Daily and cyclic parathyroid hormone in women receiving alendronate. N Engl J Med 2005;353:566-75.
Heaney RP, Recker RR. Combination and sequential therapy for osteoporosis. N Engl J Med 2005;353:624-5.
Cundy T, Davidson J, Rutland MD et al. Recombinant osteoprotegerin for Juvenile Paget’s Disease. N Engl J Med 2005;353:918-23.
Rhen T, Cidlowski JA. Antinflammatory action of glucocorticoids – new mechanisms for old drugs. N Engl J Med 2005;353:1711-23.
Kaplan MM, Gershwin ME. Primary biliary cirrhosis. N Engl J Med 2005;353:1261-73.
Petri M, Kim MY, Kalunian KC et al. Combined oral contraceptive in women with systemic lupus erythematosus. N Engl J Med 2005;353:2550-8.
2006
Firestein GS. Inhibiting inflammation in Rheumatoid Arthritis. N Engl J Med 2006;354:80-2.
Jackson RD, LaCroix AZ, Gass M et al. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med 2006;354:669-83.
Finkelstein JS. Calcium plus vitamin D for postmenopausal women – bone appetit ? N Engl J Med 2006;354:750-2.
McClung MR, Lewiecki EM, Cohen SB et al. Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 2006;354:821-31.
Tryggvason K, Patrakka J, Wartiovaara J. Hereditary proteinuria syndromes and mechanisms of proteinuria. N Engl J Med 2006;345:1387-1401.
Berman E, Nicolaides M, Maki RG et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med 2006;354:2006-13.
Seeman E, Delmas PD. Bone quality – the material and structural basis of bone strength and fragility. N Engl J Med 2006;354:2250-61.
Marcus EN. The silent epidemic – the health effects of illiteracy. N Engl J Med 2006;355:339-41.
Whyte MP. Paget’s disease of bone. N Engl J Med 206;355:593-600.
Drenth JPH, van der Meer JWM. The inflammasome – a linebacker of innate defense. N Engl J Med 2006;355:730-2.
Goldback-Masky R, Dailey NJ, Canna SW et al. Neonatal onset multisystem inflammatory disease responsive to interleukin-1 beta inhibition. N Engl J Med 2006;355:581-92.
Loeys BL, Schwarze U, Holm T et al. Aneurysm syndromes caused by mutations in the TGFbeta receptor. N Engl J Med 2006;355:788-98.
Gelb BD. Marfan’s syndrome and related disorders – more tightly connected than we thought. N Engl J Med 2006;355:841-4.
Crino PB, Nathanson KL, Henske EP. The tuberous sclerosis complex. N Engl J Med 2006;355:1345-56.
Nair KS, Rizza RA, O’Brien P et al. DHEA in elderly women and DHA and Testosterone in elderly men. N Engl J Med 2006;355:1647-59.
Bilezikian JP. Osteonecrosis of the jaw – do bisphosphonates pose a risk ? N Engl J Med 2006;355:2278-81.
Barnes AM, Chang W, Morello R et al. Deficiency of cartilage-associated protein in recessive lethal Osteogenesis Imperfecta. N Engl J Med 2006;355:2757-64.
2007
Huttenlocher A, Horwitz AR. Wound healing with electric potential. N Engl J Med 2007;356:303-4.
Tonetti MS, D’Aiuto F, Nibali L et al. Treatment of periodontitis and endothelial function. N Engl J Med 2007;356:911-20.
Jin Y, Mailloux CM, Gowan K et al. NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 2007;356:1216-25.
Gregersen PK. Modern genetics, ancient defenses, and potential therapies. N Engl J Med 2007;356:1263-6.
Larsen CM, Faulenbach M, Vaag A et al. Interleukin-1 receptor antagonist in type 2 diabetes mellitus. N Engl J Med 2007;356:1517-26.
Black DM, Delmas PD, Eastell R et al. Once-yearly Zolendronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 2007;356:1809-22.
Khosla S, Melton LJ III. Osteopenia. N Engl J Med 2007;356:2293-300.
Lipsky PE. Why does rheumatoid arthritis involve the joints ? N Engl J Med 2007;356:2419-20.
Haas D, Hoffmann GF. Mevalonate kinase deficiency and autoinflammatory disorders. N Engl J Med 2007;356:2671-3.
Neven B, Valayannopoulos V, Quartier P et al. Allogenic bone marrow transplantation in mevalonic aciduria. N Engl J Med 2007;356:2700-3.
Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.
Yates JRW, Sepp T, Matharu BK et al. Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 2007;357:553-61.
Drazen JM, Phimister EG. Publishing genomewide association studies. N Engl J Med 2007;357:496.
Barabasi AL. Network Medicine – From obesity to diseasome. N Engl J Med 2007;357:404-7.
Hunter DJ, Kraft P. Drinking from the fire hose – statistical issues in genomewide association studies. N Engl J Med 2007;357:436-9.
Canalis E, Giustina A, Bilezikian JP. Mechanism of anabolic therapies for osteoporosis. N Engl J Med 2007;357:905-16.
Plenge RM, Seielstad M, Padyukov L et al. TRAF1-C5 as a risk locus for Rheumathoid Arthritis – A genomewide study. N Engl J Med 2007;357:1199-209.
Remmers EF, Plenge RM, Lee AT et al. STAT4 and the risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus. N Engl J Med 2007;357:977-86.
Peter-Golden M, Henderson WR. Leukotrienes. N Engl J Med 2007;357:1841-54.
Calis KA, Pucino F. Zolendronic acid and secondary prevention of fractures. N Engl J Med 2007;357:1861-2.
Saag KG, Shane E, Boonen S et al. Teriparatide or alendronate in glucocorticoid induced osteoporosis. N Engl J Med 2007;357:2028-39.
2008
Allen KJ, Gurrin LC, Constantine CC et al. Iron-overload related disease in HFE hereditary hemochromatosis. N Engl J Med 2008;358:221-30.
Hom G, Graham RR, Modrek B et al. Association of Systemic Lupus Erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008;358:900-9.
Rahman A, Isenberg DA. Systemic Lupus Erythematosus. N Engl J Med 2008;358:929-39.
Lenart BA, Lorich DG, Lane JM. Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate. N Engl J Med 2008;358:1304-6.
Matsen FA III. Rotator-cuff failure. N Engl J Med 2008;358:2138-47.
Styrkarsdottir U, Halldorsson BV, Gretarsdottir S et al. Multiple genetic loci for bone mineral density and fractures. N Engl J Med 2008;358:2355-65.
Ebeling PR. Osteoporosis in men. N Engl J Med 2008;358:1474-82.
Brooke BS, Habashi JP, Judge DP et al. Angiotensin II blockade and aortic root dilatation in Marfan’s syndrome. N Engl J Med 2008;358:2787-95.
Shoback D. Hypoparathyroidism. N Engl J Med 2008;359:391-403.
Gutierrez OM, Mannstadt M, Isakova T et al. Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis. N Engl J Med 2008;359:584-92.
Hsu C. FGF-23 and outcomes research – when physiology meets epidemiology. N Engl J Med 2008;359:640-2.
Weiss LA, Shen Y, Korn JM et al. Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med 2008;359:667-75.
Han JC, Liu QR, Jones MP et al. Brain-derived neurotrophic factor and obesity in the WAGR syndrome. N Engl J Med 2008;359:918-27.
Karim Z, Gerard B, Bakouh N et al. NHERF1 mutations and responsiveness of renal parathyroid hormone. N Engl J Med 2008;359:1128-35.
Nachman RL, Rafii S. Platelets, petecchiae, and preservation of the vascular wall. N Engl J Med 2008;359:1261-70.
Rossebo AB, Pedersen TR, Boman K et al. Intensive lipid lowering withsimvastatin and ezetimibe in aortic stenosis. N Engl J Med 2008;359:1343-56.
Mefford H, Sharp A, Baker C et al. Recurrent rearrangements of chromosome 1q21.1and variable pediatric phenotypes. N Engl J Med 2008;359:1658-99.
Davis SR, Moreau M, Kroll R et al. Testosterone for low libido in postmenopausal women not taking estrogen. N Engl J Med 2008;359:2005-17.
2009
Weinstein RS, Roberson PK, Manolagas SC. Giant osteoclast formation and long-term oral bisphosphonate therapy. N Engl J Med 2009;360:53-62.
Bulun SE. Endometriosis. N Engl J Med 2009;360:268-79.
Gnant M, Mlineritsch B, Schippinger W et al. Endocrine therapy plus zolendronic acid in premenopausal breast cancer. N Engl J Med 2009;360:679-91.
Rosen CJ. Serotonin rising – The bone, brain, bowel connection. N Engl J Med 2009;360:957-9.
Laurenco D, Brauner R, Lin L et al. Mutations in NR5A1 associated with ovarian insufficiency. N Engl J Med 2009;360:1200-9.
Leopold SS. Minimally invasive total knee arthroplasty for osteoarthritis. N Engl J Med 2009;360:1749-58.
Gabrielli A, Avvedimento EV, Krieg T. Scleroderma. N Engl J Med 2009;360:1989-2003.
Noordam C, Dhir V, McNelis JC et al. Inactivating PAPSS2 mutations in a patients with premature pubarche. N Engl J Med 2009;360:2310-8.
Harousseau JL, Moreau P. Autologous hematopoietic stem cell transplantation for multiple myeloma. N Engl J Med 2009;360:2645-54.
Buchbinder R, Osborne RH, Ebeling PR et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 2009;361:557-68.
Kallmes DF, Comstock BA, Heagerty PJ et al. A randomzed trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 2009;361:569-79.
Smith MR, Egerdie B, Toriz NH et al. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med 2009;361:745-55.
Cummings SR, Martin JS, McClung MR et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009;361:756-65.
Mardis ER, Ding L, Dooling DJ et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2009;361:1058-66.
Downing JR. Cancer genome. Continuing progress. N Engl J Med 2009;361:1111-2.
Riches PL, McRorie E, Fraser WD et al. Osteoporosis associated with neutralizing antibodies against osteoprotegerin. N Engl J Med 2009;361:1459-65.
Frulloni L, Lunardi C, Simone R et al. Identification of a novel antibody associated with autoimmune pancreatitis. N Engl J Med 2009;361:2135-42.
2010
Markowitz SD, Bertagnolli MM. Molecular basis of colorectal cancer. N Engl J Med 2009;361:2449-60.
Smits P, Bolton AD, Funari V et al. Lethal Dysplasia in mice and humans lacking the Golgin GMAP-210. N Engl J Med 2010;362:206-16.
Barnes AM, Carter EM, Cabral WA et al. Lack of cyclophillin B in Osteogenesis Imperfecta with normal collagen folding. N Engl J Med 2010;362:521-8.
Cummings SR, Ensrud K, Delmas PD et al. Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med 2010;362:686-96.
Zimmerli W. Vertebral Osteomyelitis. N Engl J Med 2010;362:1022-9.
Magen D, Berger L, Coady MJ et al. A loss of function mutation in NaPiIIa and renal Fanconi’s syndrome. N Engl J Med 2010;362:1102-9.
Black DM, Kelly MP, Genant HK et al. Bisphosphonates and fractures of the subtrochanteric or diaphyseal femur. N Engl J Med 2010;362:1761-71.
Maris JM. Recent advances in Neuroblastoma. N Engl J Med 2010;362:2202-10.
Priè D, Friedlander G. Genetic disorders of renal phosphate transport. N Engl J Med 2010;362:2399-2409.
